Every year, millions of thin, flexible tubes called Central Venous Catheters (CVCs) are placed into the veins of critically ill newborns and children to deliver lifesaving therapies.

The insertion of a CVC is one of the most frequent invasive procedures performed in the Intensive Care Setting. Common types of CVC used in neonatal and pediatric care are Umbilical Venous Catheters (UVCs) and Peripherally Inserted Central Catheters (PICCs).

However, the placement and maintenance of these life lines can be difficult since there is no accurate, real-time feedback available during or after the insertion procedure. This means there are high rates of misplacement and migration of central lines during and after the insertion procedure.

40%.jpg — 40% of insertion attempts may result in a misplaced line¹

50%.jpeg — Up to 50% of correctly placed lines may migrate within 7 days²

Even when placed correctly in the insertion procedure, around half of the central lines in newborn patients can migrate to potentially dangerous positions, exposing patients to potentially devastating complications.

Stock photo (adobe licenced) - baby in NICU with blurred parent in background.jpeg — “The findings present the clinician with a clinical dilemma. If catheters are well positioned at the time of insertion, they are likely to migrate over time ..."
Hoellering A, Tshamala D, Davies MW.

Misplaced and migrated central lines lower clinical efficiency and are associated with higher risks of complications. Some of these complications can be severe and include cardiac tamponade, arrhythmia, extravasation and thrombus.

ECG TIP LOCATION SYSTEM

The Neonav® ECG Tip Location System is currently in development, and is to be used specifically for newborn and pediatric patients. Through Navi’s proprietary software and hardware solutions, the Neonav® provides clinicians with real-time tip location feedback during insertion procedure, and can be used post-procedure surveillance of catheter migration.

Features & Benefits

THE NEONAV® BENEFITS

By measuring the electrical signals from the heart (ECG) and applying sophisticated proprietary algorithms, the Neonav® provides clinicians with real-time feedback on the position of the catheter tip.

The Neonav® is completely non-invasive and can be used during the insertion procedure to improve the clinical workflow, as well as after the insertion to ensure the catheter remains in a safe position to use.

By providing real time tip location, the Neonav may improve clinical workflows and patient outcomes by:

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PATIENT

Safer insertion procedures (reduced attempts, reduced radiation)

Avoid complications (cardiac tamponade, extravasations etc..)

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CLINICAL

Improved confidence (easier insertions, ability to check migration)

Improved workflow (faster procedures, fewer complication)

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ECONOMIC

Reduced Costs of care (fewer repeated procedures & x-rays, faster insertions)

Reduced medico-legal risks (fewer complications)

Learn more

What Clinicans Are Saying

Testimonials - Clinicans

"Thanks to your inspiring innovation, children everywhere can experience brighter, healthier futures"

- CHILDREN’S NATIONAL HEALTH SYSTEM, RANKED #1 IN NEONATOLOGY

“The Neonav could revolutionise quick, accurate, cost-effective treatment for ill newborns in any setting around the world.”

- DR. MARDI STEERE, PEDIATRIC RETRIEVAL SPECIALIST & EXECUTIVE GM, MEDICAL RETRIEVAL SERVICES, ROTAL FLYING DOCTORS SERVICE

“There is nothing more annoying than waiting for an X-ray while scrubbed in a sterile environment”

- PROF. OF PEDIATRICS & BIOMEDICAL INFORMATICS, VANDERBILT NICU, TENNESSEE

References

Lean, W. L., Dawson, J. A., Davis, P. G., Theda, C., & Thio, M. (2019). Accuracy of five formulae to determine the insertion length of umbilical venous catheters. Archives of Disease in Childhood-Fetal and Neonatal Edition, 104(2), F165-F169.
Franta, J., Harabor, A., & Soraisham, A. S. (2017). Ultrasound assessment of umbilical venous catheter migration in preterm infants: a prospective study. Archives of Disease in Childhood-Fetal and Neonatal Edition, 102(3), F251-F255.
Hoellering, A., Tshamala, D., & Davies, M. W. (2018). Study of movement of umbilical venous catheters over time. Journal of Paediatrics and Child Health, 54(12), 1329-1335.